Michal H. Via Vimeo
Hi, I think what you say makes a lot of sense. It seems that hypoxemia in COVID 19 is caused by significant V/Q mismatch which is at least part of the pathophysiology of high altitude sickness. Another support for your idea comes from the fact that many physicians report a significant effect of prone positioning (beyond what would normally be expected) in patients. I too thought that ARDS without compromise of lung compliance doesn't make sense. Interestingly the renin-angiotensin system has a role in high altitude sickness and COVID 19 effects the ACE receptor.